Tetralogy of Fallot
classically combines these four defects:
1. pulmonary stenosis,
2. ventricular septal defect,
3. ventricular hypertrophy,
4. an overriding aorta.
Tetralogy of Fallot is typically treated by open heart surgery in the first year of life. Untreated, rapidly results in progressive right ventricular hypertrophy due to the increased resistance caused by narrowing of the pulmonary trunk. This progresses to heart failure which begins in the right ventricle and often leads to left heart failure and dilated cardiomyopathy. Depending on the patient's condition, palliative or complete surgical intervention can be chosen.
About the 1st model: This 3D model is based on CT angiography of a patient after a palliative surgical correction. You can recognize multiple aortopulmonary collaterals and retroesophageal right subclavian artery after previous surgical central shunt (Hillel Laks) construction.
About the 2nd model: This 3D model is based on CT angiography of a patient after a complete surgical correction. You can recognize dilated right outflow tract of the right ventricle and a residual left pulmonary artery (LPA) stenosis.
The majority of the patients seemed to live normal lives 20–37 years after the surgery.